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Global Hyaluronidase Market Analysis, Drivers, Restraints, Threats & Growth Forecast to 2030

The global hyaluronidase market size is set for rapid growth over the forecast period. In terms of revenue, the global hyaluronidase market accounted for USD 863.12 Million in 2022 and is expected to reach USD 1,326.9 Million by 2030, growing at a CAGR of 9.01% during the forecast period.

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➤ Increasing the global market’s expansion through the application of cosmetics and pharmaceuticals

Hyaluronidase is employed in ophthalmic medicinal solutions, cancer treatments, and cosmetic therapies. The anticipated demand and consequent market growth across profitable avenues are anticipated to be driven by the use of enzyme-based substrates for non-invasive disease diagnosis and its evolving position in cancer metastasis and treatment.

➤ The industry’s expansion may be hindered by the exorbitant cost of treatment and the scarcity of qualified professionals.

It is anticipated that the global hyaluronidase market will encounter obstacles, including the high cost of treatment, adverse side effects, and stringent regulations regarding the use of hyaluronidase. Furthermore, the market’s expansion is anticipated to be impeded by the scarcity of competent professionals and the potential for infections associated with the use of hyaluronidase during the forecast period.

➤ The industry is presented with numerous opportunities due to the increase in demand for minimally-invasive surgeries and the development of biosimilars.

Due to the increasing prevalence of chronic diseases, the demand for minimally invasive surgeries, and the increasing awareness of hyaluronidase applications in the pharmaceutical and cosmetic industries, the global hyaluronidase industry is anticipated to experience substantial growth in the coming years. The utilization of hyaluronidase in the treatment of cancer, surgical procedures, and ophthalmology is anticipated to drive the market. The market expansion is also bolstered by the availability of funding for research and development activities and technological advancements in drug delivery systems.

➤ The industry faces a challenge due to the stringent regulations on the use of hyaluronidase and the risk of hypersensitivity reactions.

The widespread use of hyaluronidase may also be restricted by the risk of adverse side effects. Hyaluronidase is generally thought to be safe; however, there is a possibility of hypersensitivity reactions, such as anaphylaxis, in certain patients. The development of the hyaluronidase industry may also be hindered by the strict regulations that govern its use. The regulatory landscape for hyaluronidase is inconsistent across nations, with some countries enforcing rigorous regulations regarding its use. This may restrict its availability and adoption in certain markets.

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The Global Hyaluronidase Market is segmented based on product, application and region

Global Hyaluronidase Market: Product Segment Analysis

● Animal-Derived Hyaluronidase
● Synthetic Hyaluronidase

Global Hyaluronidase Market: Application Segment Analysis

● Chemotherapy
● Dermatology
● Ophthalmology
● Plastic Surgery

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The global Hyaluronidase market profiles key players such as:

● Baxter International Inc.
● Halozyme Therapeutics Inc.
● Pfizer Inc.
● Shire Plc
● F. Hoffmann-La Roche Ltd.
● Sandoz International GmbH
● Quidel Corporation
● CSL Limited
● Pharming Group NV
● IBSA Institut Biochimique SA
● Fresenius Kabi AG
● Johnson & Johnson

???? Recent Developments

• Halozyme Therapeutics, Inc. initiated a Phase 3 clinical trial in August 2021 for its investigational drug, PEGPH20, in combination with chemotherapy in patients with previous untreated metastatic pancreatic cancer. PEGPH20 is a recombinant human hyaluronidase that is pegylated and is designed to enhance the delivery of chemotherapy by targeting the extracellular matrix of malignancies.

• In July 2021, Shire, a subsidiary of Takeda Pharmaceutical Company Limited, received FDA approval for its investigational enzyme replacement therapy, HyQvia, for the treatment of primary immunodeficiency.. HyQvia is administered subcutaneously and contains recombinant human hyaluronidase to enhance the absorption and distribution of immunoglobulin.

➤ In the forthcoming period, North America is expected to dominate the global market.

The North American region accounted for the highest market share in 2022 and is expected to experience a substantial compound annual growth rate (CAGR) during the forecast period. The primary reason for this is the growing demand for hyaluronidase in a variety of medical and cosmetic applications. The increasing prevalence of skin-related conditions, including acne, rosacea, and wrinkles, has led to the increased use of hyaluronidase in dermatology. In addition, the demand for hyaluronidase is anticipated to be driven by the increasing geriatric population in North America, particularly in the treatment of age-related conditions like osteoarthritis.

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