The global downstream processing market size was worth around USD 26.2 Billion in 2021 and is predicted to grow to around USD 88.6 Billion by 2030 with a compound annual growth rate (CAGR) of roughly 14.5% between 2022 and 2030.
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➤ Increasing pharmaceutical research and development expenditures to stimulate market expansion
Throughout the projection period, the global downstream processing market will expand due to the increasing use of sophisticated technology, diverse business strategies, and increasing pharmaceutical expenditure on research and development in the biopharmaceutical sector. In 2021, it was observed that pharmaceutical companies worldwide allocated nearly USD 200 billion to research and development in 2020, a significant increase from USD 83 million in 2019. This pertains to the Congressional Budget Office’s statistics.
➤ The market’s expansion is restricted by the scarcity of proficient professionals.
The economy’s downstream processing sector is rapidly approaching the point at which there will be an insufficient number of educated workers. Bioprocess engineering is a critical skill that is essential for individuals employed in the downstream processing industry. A growing number of CDMOs have entered the market in response to the growing demand for biosimilars. Nevertheless, the market’s advancement will be impeded by the anticipated scarcity of skilled laborers.
➤ Technological advancements offer a lucrative opportunity.
Downstream processing has been enhanced by technological and equipment advancements. The downstream processing industry’s growth is predominantly driven by advancements in acoustophoresis, specifically ultrasonic cell separation and high-precision microfluidics for label-free cell selection. Businesses are establishing a robust scientific foundation in the areas of in-line cell cleansing and rapid gene delivery, which has a significant impact on productivity.
➤ The separation and purification act’s exorbitant cost presents a significant obstacle.
The expense of separation and purification typically comprises over half of the total process expense. The downstream process is thoroughly examined in order to develop a bioprocess that is cost-effective. To achieve the necessary purity level, numerous separation and purification techniques have been implemented, thereby increasing the downstream process’s cost. Consequently, this presents a significant obstacle to the expansion of the global downstream processing market.
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The Global Downstream Processing Market is segmented based on product, application and region
Global Downstream Processing Market: Product Segment Analysis
● Chromatography Systems
● Filters
● Evaporators
● Centrifuges
● Dryers
● Others
Global Downstream Processing Market: Application Segment Analysis
● Antibiotic Production
● Hormone Production
● Antibodies Production
● Enzyme Production
● Vaccine Production
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The global Downstream Processing market profiles key players such as:
● Sartorius AG
● GE Healthcare
● Merck KGaA
● Thermofisher Scientific
● Danaher
● Repligen Corporation
● 3M
● Boehringer Ingelheim International GmbH
● Corning Incorporated
● Lonza
● Dover Corporation
● Asahi Kasei Corporation
● Eppendorf SE
???? Recent Developments:
• Sartorius Stedim Biotech acquired the chromatography division of Novasep in February 2022. This division consists of state-of-the-art equipment for the continuous production of biologics, as well as chromatography systems that are particularly well-suited for smaller biomolecules, such as oligonucleotides, peptides, and insulin.
• Agilent Technologies and Merck formed a partnership in June 2022 to address the industry’s deficit in process analytical technologies (PAT) for downstream processing. The firms’ collaboration integrates Agilent Technologies’ state-of-the-art analytical technologies (DSP) with Merck’s bioprocess portfolio to improve real-time monitoring and automated process control of critical process parameters (CPPs) and critical quality attributes (CQAs) in downstream processing.
➤ The market is anticipated to be dominated by North America during the forecast period.
The global downstream processing market is anticipated to be dominated by North America during the forecast period. The region’s expansion is ascribed to the sector’s robust healthcare infrastructure, the forthcoming government initiatives to advance bioprocess technology, and the increased utilization of downstream bioprocessing.
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